Alpha lipoic acid (ALA) (1077-28-7) Sfasali
| name: | Alfa lipoic acid (ALA) |
| CAS: | 1077-28-7 |
| tsarki | 98% |
| Formula kwayoyin: | C8H14O2S2 |
| Kwayoyin Weight: | 206.33 g / mol |
| Shawarwar Melt: | 60 – 62 ° C (140 – 144 ° F; 333 – 335 K) |
| Chemical name: | (R) -5- (1,2-Dithiolan-3-yl) ruwan pentanoic acid; Li-Lipoic acid; Alpha lipoic acid; Thioctic acid; 6,8-Dithiooctanoic acid |
| Kamancin: | (±) -α-Lipoic acid, (±) -1,2-Dithiolane-3-pentanoic acid, 6,8-Dithiooctanoic acid, DL -α-Lipoic acid, DL -6,8-Thioctic acid, Lip (S2 ) |
| InChI Key: | AGBQKNBQESQNJD-UHFFFAOYSA-N |
| Rabin Rayuwa: | Rabin rabin rayuwar da ake gudanarwa ALA ne kawai 30 min |
| Solubility: | Sananan Sauƙaƙa a cikin ruwa (0.24 g / L); Solubility a cikin ethanol 50 mg / mL |
| Yanayin Adana: | 0 - 4 C don gajere (kwanaki zuwa makonni), ko -20 C na dogon lokaci (watanni) |
| Aikace-aikace: | Ana amfani da sinadarin Alpha-lipoic acid a jiki don lalata carbohydrates da samar da kuzari ga sauran gabobin da ke cikin jiki. Alpha-lipoic acid yana aiki kamar antioxidant, wanda ke nufin yana iya ba da kariya ga ƙwaƙwalwa a ƙarƙashin yanayin lalacewa ko rauni. |
| Appearance: | Yalwa mai kama da allurai |
Alpha lipoic acid (ALA) (1077-28-7) Bayanin NMR
Idan kuna buƙatar COA, MSDS, HNMR don kowane samfurin samfur da sauran bayanai, da fatan za a tuntuɓi mu manajan talla.
Alpha Lipoic Acid (ALA) (1077-28-7)
Alpha-lipoic acid wani mahadi ne wanda aka sameshi a dabi'ance a cikin kowane sel na jikin mutum. Matsayinta na farko shine canza sukarin jini (glucose) zuwa makamashi ta amfani da oxygen, wani tsari wanda ake kira da kumburi aerobic. Hakanan ana daukar Alpha-lipoic acid a matsayin antioxidant, ma'ana cewa zai iya kawar da mahaɗan masu haɗari da ake kira 'radicals free' waɗanda ke lalata kwayoyin halitta a matakin kwayar halitta.
Abin da ke sa alpha-lipoic acid ya zama na musamman shi ne cewa yana narkewa a cikin ruwa da mai. Wannan yana nufin cewa zata iya sadar da makamashi nan take ko ta ajiye shi don amfanin gaba.
Alfa-lipoic acid kuma na iya sake amfani da “amfani” da antioxidants, gami da bitamin C, bitamin E, da kuma amino acid mai haɗuwa wanda aka sani da suna glutathione.1 Duk lokacin da waɗannan antioxidants suka keɓe mai ra’ayin ‘yanci, suna tayar da hankali kuma su zama masu tsattsauran ra’ayi da kansu. Alpha-lipoic acid yana taimaka musu wajen dawo dasu ta hanyar shan yawancin wutan lantarki da jujjuya su zuwa baya zuwa yanayin su.
Alpha-lipoic acid wani lokacin ana ɗaukar shi azaman ƙarin azaman ƙarƙashin zato zai iya inganta wasu ayyuka na rayuwa, gami da ƙona kitse, samar da sinadarai, da kula da glucose na jini. Akwai manyan shaidu na aƙalla wasu daga cikin waɗannan iƙirarin.
Alpha Lipoic Acid (ALA) (1077-28-7) fa'idodi
ciwon
An daɗe ana zaton alpha-lipoic acid na iya taimakawa wajen kula da glucose ta hanyar haɓaka saurin abin da ke narke sikari cikin jini. Wannan na iya taimakawa wajen magance ciwon sikari, cutar da ke da alaƙa da matakan hauhawar jini.
Binciken 2018 na yau da kullun da kuma nazarin maganganu na 20 gwajin gwagwarmaya na mutanen da ke fama da nakasar rayuwa (wasu suna da ciwon sukari na 2, wasu kuma suna da wasu cututtukan rayuwa) gano cewa haɓakar lipoic acid ya saukar da glucose mai azumi, haɓakar insulin, juriya na insulin, da haemoglobin na jini Matakan A1C.
Raunin jijiya
Neuropathy kalma ce ta likita da ake amfani da ita don bayyana ciwo, dimaucewa, da kuma abubuwan da basu dace ba sakamakon lalacewar jijiya. Sau da yawa, lalacewar na faruwa ne ta sanadiyyar damun ƙwayoyin cuta wanda aka ɗora akan jijiyoyin ta cututtukan da ke ci gaba kamar su ciwon sukari, cututtukan Lyme, shingles, cututtukan thyroid, gazawar koda, da HIV.
Wasu sun gaskata cewa alpha-lipoic acid, wanda aka bayar cikin wadatattun allurai, na iya magance wannan damuwa ta hanyar yin aiki mai ƙarfin antioxidant. Akwai shaidun wannan tasirin a cikin mutanen da ke fama da cutar neuropathy, mai yiwuwa yanayin rashin ƙarfi da ke cikin mutanen da ke fama da ciwon sukari.
Wani bita da aka yi a shekara ta 2012 na binciken daga Netherlands ya tabbatar da cewa yawan kwayar 600-mg na kwayar cutar alpha-lipoic acid da ake bayarwa sama da makonni uku ya ba da “raguwa mai mahimmanci kuma a asibiti cikin ciwo na neuropathic.
Kamar yadda yake tare da binciken ciwon sukari na baya, alpha-lipoic acid na baka kari Gabaɗaya ba su da tasiri ko ba su da wani tasiri ko kaɗan.
Ƙarfin Alpha-lipoic acid don haɓaka ƙona kalori da haɓaka nauyi asara yawancin gurus da masana'antun kayan abinci sun yi karin gishiri. Tare da wannan an faɗi, akwai ƙararrakin shaida cewa alpha-lipoic acid na iya yin tasiri akan nauyi, ko da yake yana da kyau.
Wani nazari na 2017 na nazarin daga Jami'ar Yale ya gano cewa abubuwan da ake amfani da su na alpha-lipoic acid, wanda ke cikin kashi daga 300 zuwa 1,800 MG kowace rana, sun taimaka wajen haifar da matsakaici. nauyi asara na 2.8 fam idan aka kwatanta da placebo.
Babu wata alaƙa tsakanin adadin kari na alpha-lipoic da adadin nauyi asara. Bugu da ƙari, tsawon lokacin jiyya ya bayyana yana rinjayar ma'aunin jikin mutum (BMI), amma ba ainihin nauyin mutum ba.
Abin da wannan ke nufi shi ne, yayin da ya bayyana za ku iya rasa nauyi sosai da alpha-lipoic acid, haɓakar jikinku na iya inganta yayin da aka maye gurbin mai da sannu-sannu da tsoka.
high Cholesterol
Alfa-lipoic acid an daɗe ana amfanuwa da yin tasiri ga nauyi da lafiya ta hanyar canza ƙirar lipid (mai) a cikin jini. Wannan ya hada da kara yawan “mai kyau” na babban kwarorode (HDL) cholesterol yayin da yake rage cholesterol da triglycerides na “mummunan” ƙananan lipoprotein (LDL). Binciken da aka yi kwanan nan ya nuna cewa mai yiwuwa ba haka bane.
A cikin binciken 2011 daga Koriya, manya 180 sun ba da 1,200 zuwa 1,800 MG na alpha-lipoic acid sun rasa kashi 21 cikin ɗari fiye da na placebo bayan makonni 20 amma ba su sami ci gaba ba a cikin duka cholesterol, LDL, HDL, ko triglycerides.
A zahiri, yawancin allurar alpha-lipoic acid da aka bayar don ƙaruwa a cikin duka cholesterol da LDL a cikin mahalarta binciken.
Fata Mai Cutar Rana
Masu kera kayan kwalliya sau da yawa suna son yin alfahari da cewa nasu kayayyakin amfana daga abubuwan "anti-tsufa" na alpha-lipoic acid. Bincike ya nuna cewa ana iya samun wasu tabbatattun ikirari. Labarin bita ya lura cewa yana da ƙarfi antioxidant kuma an yi nazari don tasirin kariya daga lalacewar radiation.
Alpha lipoic acid (ALA) (1077-28-7) amfani?
Alpha-lipoic acid ko ALA wani abu ne na halitta wanda aka yi a jiki. Yana yin ayyuka masu mahimmanci a matakin salula, kamar samar da makamashi. Matukar kana cikin koshin lafiya, jiki zai iya samar da dukkan ALA da yake bukata domin wadannan dalilai. Duk da wannan gaskiyar, an sami sha'awar amfani da kari na ALA kwanan nan. Masu ba da shawara na ALA sunyi iƙirarin da ke tattare da fa'idodi masu fa'ida don magance yanayi kamar su ciwon sukari da HIV don haɓakawa. nauyi asara.
Alpha lipoic acid (ALA) (1077-28-7) sashi
Yayinda ake la'akari da amintacce, babu wasu jagororin da ke jagorantar amfani da alpha-lipoic acid da ya dace. Ana sayar da mafi yawan maganganun baka a cikin tsari wanda ya fara daga 100 zuwa 600 MG. Dangane da yawancin shaidun yanzu, matsakaicin adadin yau da kullun har zuwa 1,800 MG ana ɗaukar amintacce a cikin manya.
Da wannan aka faɗi, komai daga nauyin jiki da shekaru zuwa aikin hanta da aikin koda suna iya tasiri abin da ke amintar da ku a zaman ɗayanku. A matsayina na babban yatsan yatsa, yi kuskure a gefen taka tsantsan kuma koyaushe a zaɓi ƙaramin kashi.
Alpha lipoic acid kari ana iya samunsu akan layi da kuma a cikin shagunan abinci da yawa na kiwon lafiya da shagunan magunguna. Don matsakaicin sha, ya kamata a ɗauki abubuwan kari akan komai a ciki.
Alpha-lipoic Acid foda na siyarwa(Inda zaka sayi Alpha-lipoic Acid foda a cikin girma)
Kamfaninmu yana jin daɗin dogon lokaci tare da abokan cinikinmu saboda muna mai da hankali kan abokin ciniki sabis da samar da manyan samfurori. Idan kuna sha'awar samfuranmu, muna da sassauƙa tare da tsara umarni don dacewa da takamaiman buƙatarku kuma lokacin saurin jagorancinmu akan umarni yana bada tabbacin za ku ɗanɗana samfurinmu akan lokaci. Har ila yau, muna mai da hankali kan ƙarin sabis ɗin ƙimar. Muna nan don tambayoyin sabis da bayani don tallafawa kasuwancin ku.
Mu ƙwararren Alfa-lipoic ne Acid foda maroki na shekaru da yawa, muna ba da samfura tare da farashi mai gasa, kuma samfurinmu yana da mafi girman inganci kuma yana fuskantar tsauraran gwaji mai zaman kansa don tabbatar da cewa yana da aminci don amfani a duk duniya.
References
- Haenen, GRMM; Bast, A (1991). "Scave na hypochlorous acid ta lipoic acid". Kimiyyar Kimiyyar Halittu. 42 (11): 2244-6. Doi: 10.1016 / 0006-2952 (91) 90363-A. PMID 1659823.
- Biewenga, GP; Haenen, GR; Bast, A (Satumba 1997). "Ilimin kimiyyar magani na antioxidant lipoic acid". Janar ilimin likitanci. 29 (3): 315–31. Doi: 10.1016 / S0306-3623 (96) 00474-0. PMID 9378235.
- Schupke, H; Hambari, R; Bitrus, G; Hermann, R; et al. (Yuni 2001). "Sabbin hanyoyin rayuwa na alpha-lipoic acid". Magungunan ƙwayoyi da Zama. 29 (6): 855-62. PMID 11353754.
- Acker, DS; Wayne, WJ (1957). "Aiki mai aiki da tasiri α-lipoic acid". Jaridar American Chemical Society. 79 (24): 6483–6487. Doi: 10.1021 / ja01581a033.
- Hornberger, CS; Heitmiller, RF; Gunsalus, IC; Schnakenberg, GHF; et al. (1952). "Shirye-shiryen roba na lipoic acid". Jaridar American Chemical Society. 74 (9): 2382. doi: 10.1021 / ja01129a511.
