α-ketoglutaric (328-50-7) (71686-01-6) - Maƙerin masana'anta

-ketoglutaric

Cofftek yana da damar samar da taro da wadatar Calcium 2-oxoglutarate da Alpha-Ketoglutaric Acid a ƙarƙashin yanayin cGMP.

Banki na Cofttek

Sayi α-ketoglutaric foda

Zazzage albarkatun

Menene Alpha-Ketoglutaric Acid (328-50-7)?

Alpha-ketoglutaric acid wani mahaɗan halitta ne wanda aka samo shi ta hanyar jikin mutum. Hakanan ana samunsa azaman ƙarin abincin abincin, alpha-ketoglutaric acid yana taka muhimmiyar rawa a cikin zagayen Krebs (jerin halayen sinadarai da ake amfani da su don sakin makamashin da aka adana). Abubuwan kari na Alpha-ketoglutaric acid ana yin su ne don bayar da fa'idodi daban-daban na kiwon lafiya, gami da haɓaka wasannin motsa jiki da haɓaka kuzari.

Alpha-Ketoglutaric Acid (328-50-7) fa'idodi

Tare da faɗin haka, aan binciken farko da farko sun nuna fa'idodi mai amfani da alpha-ketoglutaric acid supplementation. Ga abin da wasu daga cikin binciken na yanzu ke cewa:
①Cutar Ciwon Koda
An yi amfani da Alpha-ketoglutaric acid tun daga ƙarshen-1990s don taimakawa wajen rushewa da kuma sha furotin a cikin mutane akan hemodialysis waɗanda ke buƙatar rage cin abinci mai gina jiki. Shaidu na baya-bayan nan sun nuna cewa yana iya jinkirta buƙatuwar dialysis a cikin mutanen da ke fama da cutar koda ta ci gaba (CKD).

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Source Amintacce

PubMed Central

Babban mutunta bayanai daga Cibiyoyin Lafiya na Ƙasa
Je zuwa tushen

Bisa ga binciken 2017 a cikin mujallar PLoS One, masu bincike sun gano kuma sun bi mutane 1,483 tare da ci gaba na CKD wadanda suka yi amfani da wani kari na alpha-ketoglutaric acid da ake kira Ketosteril. Matsakaicin tsawon lokacin bin diddigin ya kasance shekaru 1.57.
Idan aka kwatanta da madaidaitan saitin mutanen da ba su ɗauki kari ba, waɗanda suka yi ba su da yuwuwar buƙatar dialysis na dogon lokaci. Amfanin ya bazu ga waɗanda suka ɗauki fiye da allunan 5.5 kowace rana, yana nuna tasirin ya dogara da kashi.
Duk da ingantaccen binciken, ba a san irin rawar da alpha-ketoglutaric acid ya taka ba idan aka kwatanta da sauran kayan aikin kari. Ana buƙatar ƙarin bincike.

HealthCutar Lafiya ta hanji
Alpha-ketoglutaric acid kari an yi imani da su zama anticatabolic, ma'ana cewa yana jinkiri ko hana ko catabolism (rushewar kyallen takarda). Ta hanyar ma'anar, tsarin catabolic ya saba wa tsarin anabolic (wanda aka gina kyallen takarda).
Wani bincike na 2012 a cikin Jarida na Italiyanci na Kimiyyar Dabbobi ya ruwaito cewa alpha-ketoglutaric acid ya hana rushewar hanji a cikin berayen da ke ciyar da abinci marar gina jiki na kwanaki 14. Maimakon fuskantar lalacewa ga ɗan yatsa-kamar villi na hanji - sakamakon da ake tsammani - berayen da aka ciyar da alpha-ketoglutaric acid ba su da wani lahani na bayyane idan aka kwatanta da berayen da ba su da.
Bugu da ƙari, berayen da aka ba da kari sun sami damar ci gaba da ci gaban al'ada duk da ƙarancin furotin. An ba da mafi girman allurai zuwa sakamako mafi kyau.
Binciken ya bayyana yana tallafawa tasirin anticatabolic na alpha-ketoglutaric acid. Baya ga aikace-aikacen sa a cikin cututtukan koda na yau da kullun, alpha-ketoglutaric acid na iya taimakawa mutanen da ke da toxemia na hanji da cututtukan malabsorption kamar cutar celiac. Ana buƙatar ƙarin bincike.

Wasannin motsa jiki
Sabanin haka, tasirin anticatabolic na alpha-ketoglutaric acid ya bayyana ya ragu lokacin da aka yi amfani da shi don manufar ci gaban tsoka da wasan motsa jiki.
Bisa ga binciken 2012 a cikin Journal of the International Society of Sports Nutrition , alpha-ketoglutaric acid ba shi da wani tasiri mai tasiri akan ko dai ƙarfin tsoka ko ƙarfin motsa jiki a cikin maza na 16 da aka ba da aikin horo na juriya.

(2) ↗

Source Amintacce

PubMed Central

Babban mutunta bayanai daga Cibiyoyin Lafiya na Ƙasa
Je zuwa tushen

Don wannan binciken, an ba rabin mazan 3,000-miligrams (mg) na alpha-ketoglutaric acid, yayin da sauran rabin an ba su wuribo minti 45 kafin yin aikin buga benci da motsa jiki. A mako mai zuwa, an jujjuya abubuwan da aka kayyade, tare da kowane rabin samun madadin magani.
Ayyukan wasan motsa jiki sun dogara ne akan jimlar ƙarar kaya (TLV) na atisayen da aka yi tare da ƙimar zuciya da aka riga aka yi da bayan motsa jiki. Abin da waɗannan binciken ke nunawa shine rashin amsawar catabolic ba daidai ba ne da amsawar anabolic, musamman a tsakanin 'yan wasa.

Alpha-Ketoglutaric Acid (328-50-7) amfani?

A aikin tiyatar zuciya, alpha-ketoglutaric acid wani lokaci ana isar da shi ta hanyar jijiya (cikin jijiya) don rage lalacewar tsokar zuciya saboda raguwar kwararar jini. Yin hakan na iya inganta kwararar jini zuwa koda bayan tiyatar.
Amfani da shi azaman kari ba shi da tabbas sosai. Kwararrun likitocin sun yi imanin cewa alpha-ketoglutaric acid na iya bi da ko hana nau'ikan yanayin kiwon lafiya iri-iri, gami da:
  • cataracts
  • Kwarar cutar koda
  • Hepatomegaly (faɗaɗa hanta)
  • Toxemia na hanji
  • Maganin baka
  • osteoporosis
  • Tendinopathy
  • Yisti kamuwa da cuta
Saboda rawar da yake takawa wajen fitar da kuzarin da aka adana, alpha-ketoglutaric acid galibi ana tallata shi azaman kari na wasan kwaikwayo. Wasu masu ba da goyan baya ma sun tabbatar da cewa tasirin antioxidant na kari na iya rage tsufa.

(3) ↗

Source Amintacce

PubMed Central

Babban mutunta bayanai daga Cibiyoyin Lafiya na Ƙasa
Je zuwa tushen

Kamar yadda sau da yawa yakan faru tare da kari waɗanda ke da'awar kula da yanayi marasa alaƙa da yawa, shaidar da ke goyan bayan waɗannan da'awar ba ta da ƙarfi. Wasu, kamar kaddarorin "anti-tsufa" na kari (wanda ya danganta da binciken 2014 da ya shafi tsutsotsi nematode), iyaka akan abin da ba zai yuwu ba.

Alpha-Ketoglutaric Acid (328-50-7) sashi

Ana samun kariyar Alfa-ketoglutaric acid a cikin kwamfutar hannu, capsule, da foda kuma ana iya samun su cikin sauƙi akan layi ko a cikin shagunan ƙwararrun kayan abinci na abinci.
Babu ƙa'idodin duniya don dacewa da amfani da alpha-ketoglutaric acid. Ana sayar da kari a yawancin allurai daga 300 milligrams (mg) zuwa MG 1,000 da ake sha sau ɗaya kowace rana tare da ko ba tare da abinci ba. An yi amfani da allurai har zuwa 3,000 MG a cikin binciken ba tare da wani tasiri ba.

Alpha-Ketoglutaric Acid (328-50-7) yiwuwar sakamako mai illa

Alpha-ketoglutaric acid ana ɗaukarsa lafiya kuma mai jurewa. Nazarin da ke bincikar tasirin alpha-ketoglutaric acid ya ba da rahoton ƙananan alamun rashin lafiya bayan shekaru uku na amfani.
A matsayin wani fili da aka yi daga amino acid marasa mahimmanci, alpha-ketoglutaric acid ba wani abu bane wanda zaku iya wuce gona da iri akai-akai. Duk wani abin da ya wuce gona da iri a cikin jiki ko dai za a fitar da shi cikin fitsari ko kuma a karbe shi zuwa tushen ginin amino acid don wasu dalilai.

(4) ↗

Source Amintacce

PubMed Central

Babban mutunta bayanai daga Cibiyoyin Lafiya na Ƙasa
Je zuwa tushen

Da wannan ya ce, ba a kafa amincin alpha-ketoglutaric acid a cikin mata masu juna biyu, masu shayarwa, da yara ba. Wannan ya haɗa da yara waɗanda ke fama da rikice-rikice na metabolism kamar ƙarancin alpha-ketoglutarate dehydrogenase (wanda matakan alpha-ketoglutaric acid ke ƙaruwa da yawa).

Alpha-Ketoglutaric Acid foda don siyarwa (Inda zaka Sayi Alpha-Ketoglutaric Acid foda a cikin yawa)

Kamfaninmu yana jin daɗin haɗin kai tare da abokan cinikinmu saboda mun mai da hankali kan sabis na abokin ciniki da samar da samfuran manyan kayayyaki. Idan kuna da sha'awar samfurinmu, muna jujjuya tare da ƙirƙirar umarni don dacewa da takamaiman buƙatunku da lokacin jagoranmu na sauri akan umarni wanda zai ba ku tabbacin ku ɗanɗano samfurinmu akan lokaci. Hakanan muna mai da hankali kan ayyukan ƙara ƙimar. Muna samuwa don tambayoyin sabis da bayani don tallafawa kasuwancin ku.
Mu masu sana'a ne Alpha-Ketoglutaric Acid foda maroki na shekaru da yawa, muna samar da samfurori tare da farashin gasa, kuma samfurinmu yana da mafi girman inganci kuma yana fuskantar gwaji mai zaman kansa don tabbatar da cewa yana da aminci don amfani a duniya.

reference:

  1. Abrahams JP, Leslie AG, Lutter R, Walker JE. Tsari a 2.8 resolutionudurin F1-ATPase daga bovine zuciya mitochondria. Yanayi. 1994; 370: 621-628. Doi: 10.1038 / 370621a0.
  2. Alpers DH. Glutamine: Shin bayanan suna tallafawa abin da ke haifar da ƙarin glutamine a cikin mutane? Gastroenterology. 2006; 130: S106 – S116. Doi: 10.1053 / j.gastro.2005.11.049.
  3. Ashkanazi J, Carpertier Y, Michelsen C. Muscle da plasma amino acid bayan rauni. Ann Surg. 1980; 192: 78-85. Doi: 10.1097 / 00000658-198007000-00014.