-ketoglutaric

Cofftek yana da damar samar da taro da wadatar Calcium 2-oxoglutarate da Alpha-Ketoglutaric Acid a ƙarƙashin yanayin cGMP.

Menene Alpha-Ketoglutaric Acid (328-50-7)?

Alpha-ketoglutaric acid wani mahaɗan halitta ne wanda aka samo shi ta hanyar jikin mutum. Hakanan ana samunsa azaman ƙarin abincin abincin, alpha-ketoglutaric acid yana taka muhimmiyar rawa a cikin zagayen Krebs (jerin halayen sinadarai da ake amfani da su don sakin makamashin da aka adana). Abubuwan kari na Alpha-ketoglutaric acid ana yin su ne don bayar da fa'idodi daban-daban na kiwon lafiya, gami da haɓaka wasannin motsa jiki da haɓaka kuzari.

Alpha-Ketoglutaric Acid (328-50-7) fa'idodi

Tare da faɗin haka, aan binciken farko da farko sun nuna fa'idodi mai amfani da alpha-ketoglutaric acid supplementation. Ga abin da wasu daga cikin binciken na yanzu ke cewa:
①Cutar Ciwon Koda
Anyi amfani da sinadarin Alpha-ketoglutaric acid tun a karshen shekarun 1990s don taimakawa karyewa da kuma shan furotin a cikin mutane akan hemodialysis wadanda ke buƙatar cin abinci mai ƙarancin furotin. Bayanai na baya-bayan nan sun nuna cewa hakan na iya jinkirta bukatar wankin koda a jikin mutanen da ke fama da cutar koda mai tsanani (CKD). Dangane da nazarin 2017 a cikin mujallar PLoS One, masu bincike sun gano kuma sun bi mutane 1,483 tare da CKD mai ci gaba waɗanda ke amfani da ƙarin alpha-ketoglutaric acid mai suna Ketosteril. Matsakaicin tsawan bibiyar ya kasance shekaru 1.57. Idan aka kwatanta da daidaitattun mutane waɗanda ba su ɗauki ƙarin ba, waɗanda suka yi ba za su iya buƙatar wankin koda na dogon lokaci ba. Fa'idodin da aka ba kawai ga waɗanda suka ɗauki fiye da allunan 5.5 kowace rana, suna nuna alamun sun kasance masu dogaro da kashi. Duk da kyakkyawan binciken, ba a san irin rawar da alpha-ketoglutaric acid ya taka ba idan aka kwatanta da sauran kayan aikin. Ana buƙatar ci gaba da bincike.

HealthCutar Lafiya ta hanji
Abubuwan kari na Alpha-ketoglutaric acid ana yin amannar cewa suna dauke da cutar, wanda ke nuna cewa yana raguwa ko hanawa ko kuma haifarda cuta (lalacewar kyallen takarda). Ta hanyar ma'ana, tsarin haɓaka yana kishiyar tsarin anabolic (wanda aka gina kyallen takarda). Wani bincike da aka gudanar a shekara ta 2012 a mujallar ilimin kimiyyar dabbobi ta kasar Italiya ya ruwaito cewa alpha-ketoglutaric acid ya hana karyewar hanji a jikin berayen da ke ciyar da abinci mara gina jiki tsawon kwanaki 14. Maimakon fuskantar lalacewar yatsun hanji kamar na hanji — sakamakon da ake tsammani — berayen da suka ciyar da alpha-ketoglutaric acid ba su da wata illa ta zahiri idan aka kwatanta da berayen da ba su ba. Bugu da ƙari, berayen sun ba da abubuwan haɓaka sun iya kula da ci gaban al'ada duk da rashin ƙarancin furotin. Doananan allurai da aka bayar har ma da kyakkyawan sakamako. Abubuwan binciken sun bayyana don tallafawa alpha-ketoglutaric acid na maganin cutar kansa. Baya ga aikace-aikacen ta a cikin cututtukan koda, alpha-ketoglutaric acid na iya taimaka wa mutane da cutar toxemia ta hanji da cututtukan malabsorption kamar cutar celiac. Ana buƙatar ci gaba da bincike.

Wasannin motsa jiki
Sabanin haka, cututtukan cututtukan cututtukan alpha-ketoglutaric sun bayyana kamar sun faɗi ƙasa yayin amfani da su don manufar haɓakar tsoka da wasan motsa jiki. Dangane da nazarin 2012 a cikin Jaridar International Society of Sports Nutrition, alpha-ketoglutaric acid ba shi da wani tasirin azo a gani ko dai ƙarfin tsoka ko kuma jimiri a cikin maza 16 da aka ɗorawa horo. Don wannan binciken, rabin mutanen an basu 3,000-milligram (mg) na alpha-ketoglutaric acid, yayin da sauran rabin aka basu placebo mintuna 45 kafin yin aikin buga benci da atisayen buga kafa. Mako mai zuwa, an juya abubuwan kari, tare da kowane rabi suna samun madadin maganin. Wasannin motsa jiki ya dogara ne akan jimlar nauyin nauyi (TLV) na darussan da aka yi cikin jituwa tare da bugun zuciya kafin-da-motsa jiki. Abin da waɗannan binciken suka nuna shine rashin amsawar catabolic ba ɗaya ba ne da amsa anabolic, musamman tsakanin 'yan wasa.

Alpha-Ketoglutaric Acid (328-50-7) amfani?

A tiyatar zuciya, alpha-ketoglutaric acid a wasu lokuta akan kawo shi cikin jijiyoyi (cikin jijiya) don rage lalacewar jijiyoyin zuciya saboda raguwar gudan jini. Yin hakan na iya inganta gudan jini zuwa koda bayan tiyatar. Amfani da shi azaman ƙarin bashi da tabbas. Sauran likitocin sunyi imanin cewa alpha-ketoglutaric acid na iya magance ko hana nau'ikan yanayin kiwon lafiya, gami da:
  • cataracts
  • Kwarar cutar koda
  • Hepatomegaly (faɗaɗa hanta)
  • Toxemia na hanji
  • Maganin baka
  • osteoporosis
  • Tendinopathy
  • Yisti kamuwa da cuta
Saboda rawar da yake takawa wajen sakin makamashi da aka adana, alpha-ketoglutaric acid galibi ana tallata shi azaman ƙarin aikin wasan motsa jiki. Wasu masu goyon bayan har ma suna tabbatar da cewa tasirin abubuwan kara kuzari na iya rage tsufa. Kamar yadda yake yawanci lamarin tare da abubuwan kari waɗanda ke da'awar magance yanayi da yawa da ba su da alaƙa, hujjojin da ke tallafawa waɗannan iƙirarin masu rauni ne. Wasu, kamar kaddarorin "anti-tsufa" na ƙari (wanda ya ta'allaka ne akan nazarin 2014 wanda ya shafi tsutsotsi masu nematode), kan iyaka akan yiwuwar.

Alpha-Ketoglutaric Acid (328-50-7) sashi

Ana samun abubuwan kari na Alpha-ketoglutaric acid a cikin kwamfutar hannu, kwantena, da kayan hada foda kuma ana iya samun su ta hanyar yanar gizo ko kuma a shagunan da suka kware kan kayan abincin. Babu wasu jagororin duniya game da amfanin alpha-ketoglutaric mai dacewa. Ana sayar da kari a cikin jigilar abubuwa daga 300 milligrams (MG) zuwa 1,000 MG da aka sha sau ɗaya kowace rana tare da ko ba tare da abinci ba. An yi amfani da allurai har zuwa 3,000 MG a cikin karatun ba tare da wata illa ba.

Alpha-Ketoglutaric Acid (328-50-7) yiwuwar sakamako mai illa

Alfa-ketoglutaric acid ana ɗauke dashi amintacce kuma mai jurewa sosai. Nazarin binciken tasirin alpha-ketoglutaric acid ya ba da rahoton 'yan alamun bayyanar cututtuka bayan shekaru uku na amfani. A matsayin mahadi wanda aka samar dashi daga amino acid mara mahimmanci, alpha-ketoglutaric acid ba wani sinadari bane wanda zaka iya shan saukinsa a kai a kai. Duk wani abin da ya wuce gona da iri a cikin fitsari ko kuma zai shiga cikin asalin amino acid don wasu dalilai. Tare da cewa, ba a tabbatar da amincin alpha-ketoglutaric acid a cikin mata masu juna biyu, masu shayarwa, da yara ba. Wannan ya hada da yara masu fama da cuta mai saurin narkewa kamar rashin ƙarancin alpha-ketoglutarate (wanda a cikin sa ake ɗaga matakan alpha-ketoglutaric acid).

Alpha-Ketoglutaric Acid foda don siyarwa (Inda zaka Sayi Alpha-Ketoglutaric Acid foda a cikin yawa)

Kamfaninmu yana jin daɗin hulɗa na dogon lokaci tare da abokan cinikinmu saboda muna mai da hankali kan sabis na abokin ciniki da kuma samar da kyawawan kayayyaki. Idan kuna sha'awar samfuranmu, muna da sassauƙa tare da tsara umarni don dacewa da takamaiman buƙatarku kuma lokacin saurin jagorancinmu akan umarni yana bada tabbacin za ku ɗanɗana samfurinmu akan lokaci. Hakanan muna mai da hankali kan ƙarin sabis ɗin ƙima. Muna nan don tambayoyin sabis da bayani don tallafawa kasuwancin ku. Mu ƙwararren mai samarda furotin ne na Alpha-Ketoglutaric Acid na shekaru da yawa, muna samar da kayayyaki da farashi mai fa'ida, kuma samfuran mu yana da inganci kuma yana shan tsayayye, gwaji mai zaman kansa don tabbatar da cewa yana da aminci ga amfani a duniya.

reference:

  1. Abrahams JP, Leslie AG, Lutter R, Walker JE. Tsari a 2.8 resolutionudurin F1-ATPase daga bovine zuciya mitochondria. Yanayi. 1994; 370: 621-628. Doi: 10.1038 / 370621a0.
  2. Alpers DH. Glutamine: Shin bayanan suna tallafawa abin da ke haifar da ƙarin glutamine a cikin mutane? Gastroenterology. 2006; 130: S106 – S116. Doi: 10.1053 / j.gastro.2005.11.049.
  3. Ashkanazi J, Carpertier Y, Michelsen C. Muscle da plasma amino acid bayan rauni. Ann Surg. 1980; 192: 78-85. Doi: 10.1097 / 00000658-198007000-00014.