Palmitoylethanolamide foda

Palmitoylethanolamide foda bidiyo

Palmitoylethanolamide foda (PEA) foda Sfasali

Palmitoytaniyalam (544-31-0) Bayanin NMR

Idan kuna buƙatar COA, MSDS, HNMR don kowane samfurin samfur da sauran bayanai, da fatan za a tuntuɓi mu manajan talla.

Palmitoylethanolamide is a endogenic fatty acid amide wanda ya faɗi ƙarƙashin aji na Agonists Factor Agonists. Yana faruwa a zahiri a cikin abinci kamar waken soya, gyada lecithin, da jikin mutum.

An fara gano Palmitoylethanolamide a farkon shekarun 1940. Masana kimiyya da farko sun gano cewa shan ruwan gwaiwar kwai yana inganta lafiyar rigakafi ga yara kuma yana rage haɗarin kamuwa da zazzabin rheumatic. Wani bincike ya tabbatar da cewa kwai gwaiduwa na dauke da wani fili na musamman watau PEA. Hakanan ana samun PEA a cikin abinci gabaɗaya kamar gyada da waken soya, waɗanda ke taimakawa samar da rigakafi mai ƙarfi da amfanin kiwon lafiya.

Bayan samun sa a wasu abinci, PEA yana faruwa a jikin mu ta halitta. An samar da sinadarin cikin jikin mu ta yawancin sel din mu a matsayin wani bangare na amsar rigakafin lafiya. PEA musamman jikin mu ne ya yi shi don mayar da kumburi. An san shi don sarrafa ciwon mu a cikin jiki ta hanyar kare tsarin garkuwar jikin mu daga wuce gona da iri kuma yana inganta ingantaccen rigakafin kamuwa da cutar kumburi a cikin jiki.

Palmitoylethanolamide foda galibi ana amfani dashi azaman magani don ciwo, fibromyalgia, ciwon neuropathic, sclerosis da yawa, ramin ramin carpal, da sauran yanayi da yawa.

Palmitoylethanolamide da dangin Cannabinoid

Palmitoylethanolamide ba lallai ba ne ya fito daga cannabis amma ana iya ɗaukarsa wani ɓangare na dangin cannabinoid. PEA yana aiki a cikin hanya mai kama da CBD (cannabidiol), wanda shine ɗayan manyan mahadi a cikin cannabis amma ba shi da tasirin psychogenic. Abubuwan CBD sun shahara sosai a kwanakin nan kuma ana samun su a kusan komai daga mai zuwa creams, da samfuran abinci. CBD Hakanan ana amfani da samfuran don yawancin yuwuwar lafiya fa'idodi, gami da lafiyar hankali, jijiya, da lafiyar haɗin gwiwa.

PEA shima cannabinoid ne, amma ana nazarin shi azaman karshencannabinoid kamar yadda aka yi a cikin jiki. Koyaya, ya bambanta da cannabidiol da tetrahydrocannabinol saboda jiki baya yin waɗannan sunadarai.

Kayan aikin

Palmitoylethanolamide yana haifar da ƙona mai, mai haɓaka kuzari, da alpha PPAR mai kumburi. Lokacin da aka kunna waɗannan mahimman furotin, PEA ta dakatar da aikin kwayoyin halittar da ke iya haɓaka kumburi kuma ta rage samar da abubuwa masu kumburi da yawa. Har ila yau, PEA tana rage ayyukan halittar FAAH wanda ke rushe cannabinoid anandamide na halitta kuma yana haɓaka matakan anandamide a cikin jiki. Anandamide yana da alhakin rage zafin ku, kwantar da hankalin ku, da haɓaka shakatawa a cikin jikin ku.

Hakanan an san PEA tana ɗaure sel jikin kuma tana rage zafi da kumburi. Ya ƙunshi palmitic acid a cikin tsarin sa, wanda ke taimaka wa jiki yin Palmitoylethanolamide a cikin jiki.

A cewar wasu masana kimiyya, kawai ƙara yawan amfani da acid palmitic ba zai shafi samar da PEA ba. Wannan saboda jikin ku zai yi amfani da PEA ne kawai a cikin jikin ku kawai lokacin da yake buƙatar warkar da kumburin ku ko ciwo. Wannan yana haifar da matakan PEA a cikin jiki yawanci yana canzawa cikin yini.

Hanya mafi kyau don samun fa'idar PEA shine ta hanyar cin abinci mai wadatar PEA ko daidaitattun kari.

Palmitoylethanolamide foda fa'idodi da aikace -aikace

An tabbatar da PEA yana da abubuwan rage zafi da kaddarorin kumburi kuma an yi amfani da shi don gudanar da ciwo na yau da kullun tsakanin manya da mawuyacin yanayin asibiti. Misali, yana iya ba da taimako mai taimako kamar mai taimakawa don magance ƙananan ciwon baya a cikin tsofaffi marasa lafiya ko kuma ana iya amfani da shi kaɗai don gudanar da ciwo mai ɗorewa a cikin marasa lafiya marasa lafiya a maimakon magungunan maganin gargajiya waɗanda ke da haɗarin haɗarin illa.

An nuna sakamako mai ban al'ajabi a cikin maganin radiculopathies marasa aikin tiyata tare da ƙirar ƙirar ƙira mai ƙarfi na PEA da haɗin haɗin gwiwa tare da alpha-lipoic acid don rage cututtukan prostatitis na yau da kullun/ciwo na ƙashin ƙugu.

Da ke ƙasa akwai wasu fa'idodi masu kyau na PEA:

· Taimakon Raɗa

Akwai wasu shaidu da ke tabbatar da ikon PEA na rage tsananin ciwo. An bincika PEA a cikin mutane sama da dubu 6 da gwajin asibiti 30 tun daga shekarun 1070. Duk da haka, binciken sau da yawa ya kasa rarrabewa tsakanin ciwon neuropathic da wanda ba neuropathic ba. The ab advantagesbuwan amfãni daga Palmitoylethanolamide don ciwon neuropathic ba su da haske saboda ƙarancin isasshen bayani zuwa yau.

Wata ƙuntatawa ita ce mafi yawan waɗannan karatun ba su da ikon sarrafa wuribo kuma ana buƙatar ingantaccen bincike don yanke shawarar tasirin PEA a cikin sauƙaƙe nau'ikan jin zafi.

A cikin binciken nazarin mutane 12, kariyar PEA ya nuna tasiri a cikin rage ƙarfin ciwon na kullum da neuropathic ba tare da wani mummunan sakamako ba. Wadancan mutane 12 galibi ana ba su kari na PEA tare da allurai tsakanin 200 zuwa 1200 MG/rana sama da makonni 3 zuwa 8. Ƙarin ya ɗauki kimanin makonni biyu don cimma yanayin rage radadin ciwo. Shan shi na tsawon lokaci yana ciyar da illolin sa ba tare da haifar da wani illa ba.

Wani binciken da aka yi tare da 300 ko 600 MG/rana na PEA ya nuna raguwar ƙarfi a cikin cututtukan sciatica a cikin gwaji mai mahimmanci na mutane 600. PEA ta rage zafi sama da 50% a cikin makwanni 3 kacal, wanda da wuya a samu tare da mafi yawan masu rage zafin ciwo.

· Lafiyar kwakwalwa da sabuntawa

Hakanan an san PEA yana da fa'ida ga cututtukan neurodegenerative da bugun jini. Ana ganin ƙarin don inganta aikin kwakwalwa ta hanyar taimakawa ƙwayoyin kwakwalwa don tsira da rage kumburi.

A cikin nazarin marasa lafiya 250 na bugun jini, ƙirar PEA tare da luteolin ya nuna alamun ingantaccen murmurewa. Hakanan an yi shelar yana da fa'ida mai amfani ga lafiyar kwakwalwa mai kyau, ƙwarewar fahimi, da aikin kwakwalwa na yau da kullun. An lura da tasirin bayan kwanaki 30 na kari kuma lokacin bayan watanni biyu na ƙarin, an lura da ƙarin haɓakawa.

Dukansu tare da luteolin kuma shi kaɗai, an ga PEA don hana cutar Parkinson a cikin mice lokacin amfani da luteolin. Yana rage lalacewar kwakwalwa ta hanyar kare kwayoyin halittar dopamine. Koyaya, ana buƙatar daidaitattun karatun asibiti don tabbatar da waɗannan binciken.

Wani binciken ya nuna cewa PEA tare da luteolin ya taimaka wajen haɓaka abubuwan neurotrophic kamar BDNF & NGF waɗanda ƙananan furotin masu ƙarfi masu amfani don ƙirƙirar sabbin ƙwayoyin kwakwalwa. Yana haɓaka ikon kwakwalwa don sake sabunta sabbin sel da kyallen takarda bayan ɓarna da lalacewar kashin baya ko kwakwalwa. Lokacin da aka yi amfani da PEA tare da luteolin a cikin beraye yana haɓaka warkar da jijiyoyi a cikin mice tare da raunin kashin baya.

Saboda abin da ya faru na cannabinoids a cikin PEA, tasirin ya nuna haɓakawa a cikin halayen marasa lafiya, yanayi. Ya nuna raguwar haɗarin kamawa a cikin mice. Duk da haka, har yanzu ba a bincika illar da take samu a jikin mutane ba kuma ana buƙatar ƙarin binciken don tabbatar da hakan.

· Illolin Zuciya

Ciwon zuciya na faruwa ne sakamakon toshewar hanyoyin jini da ke kaiwa zuwa zuciya. An san PEA don warkar da lalacewar kyallen takarda na zuciya da haɓaka zub da jini zuwa zuciya wanda ke taimakawa rage cututtukan bugun zuciya. Nazarin a cikin beraye ya kuma nuna raguwar matakan cytokine mai kumburi a cikin zukata.

Amfani da PEA kuma ya rage matakin hawan jini a cikin beraye kuma ya hana lalacewar koda ta hanyar rage abubuwan kumburi. Ta hanyar taƙaita jijiyoyin jini, PEA yana da tasiri don toshe enzymes da masu karɓa waɗanda ke haɓaka hawan jini.

· Alamun bakin ciki

A cikin binciken da aka yi kwanan nan, mutane 58 da ke fama da baƙin ciki an yi musu maganin PEA. An ba marasa lafiya allurai na 1.2 gm a kowace rana sama da makonni 6. Wannan ya haifar da saurin haɓaka yanayi da alamomin gaba ɗaya. PEA lokacin da aka kara shi zuwa maganin hana kumburin ciki watau, citalopram, ya saukar da alamun bacin rai ta daidaitaccen kashi 50%.

· Alamomin ciwon sanyi

Wani binciken ya nuna PEA ya zama ingantaccen magani don yaƙar ƙwayar mura da ke haifar da mura. A wasu binciken farko na sama da mutane dubu 4, PEA ta sami damar nuna tasiri mai kyau a cikin rigakafi kuma ta taimaka rage alamomin mura kamar marasa lafiya.

A cikin wani binciken, an ba matasa sojoji 900 kimanin 1,200 MG na PEA wanda ya rage tsawon lokacin sanyi da warkar da alamomi kamar ciwon makogwaro, hanci, zazzabi, da ciwon kai.

· Ciwan ciki

A ƙarshe amma ba aƙalla an yi nasarar amfani da PEA don tayar da alamun cututtukan hanji mai kumburi (IBS) a cikin dabbobi. Ci gaban PEA lokacin da aka gwada shi a cikin beraye tare da kumburin hanji na yau da kullun, ya taimaka daidaita tsarin hanji kuma ya hana lalacewar rufin hanji.

Lalacewar hanji ko kumburi yana haifar da ulcerative colitis wanda zai iya haifar da haɗarin cutar kansa. Amfani da PEA ya dakatar da ƙwayar hanji ta al'ada daga haɓaka ƙwayar cuta a cikin beraye. PEA yana rage cytokines masu kumburi da haɓaka neutrophils da ƙwayoyin rigakafi waɗanda ke ƙarfafa alamun lalacewar hanji.

Tushen abinci na Palmitoylethanolamide

Kodayake PEA cikakken kitse ne mai kitse, gami da ƙarin kitse mai ƙima a cikin abincin ku zai fi cutarwa fiye da kyau. Cin abinci mai yawan kitse mai cike da kitse ba zai ƙara samar da sinadarin PEA na jikin ku ba maimakon haka zai ƙara haɗarin kamuwa da cututtuka daban -daban na yau da kullun.

Abinci kamar kayayyakin soya, lecithin soya, gyada, da alfalfa wasu manyan hanyoyin PEA ne. Mutanen da ke da alaƙar goro dole ne su tsallake gyada su cinye wasu abinci. Kwai gwaiduwa wata kyakkyawar hanya ce kuma mutanen da ba su da hankali ga ƙwai za su iya cinye su. Masu amfani kuma za su iya yin la’akari da ɗaukar kariyar PEA tunda sun kasance mafi aminci kuma zaɓi mai inganci.

PEA tana kari sashi & aminci

Dangane da karatun asibiti, aƙalla 600 MG/rana na iya buƙata don sauƙaƙe ciwon jijiya, kuma ana iya amfani da allurai na 1.2 g/rana don magance ciwon jijiya na masu ciwon sukari.

Ga masu ciwon sukari da ke fama da matsalolin ido, allurai har zuwa 1.8 g/rana sun yi tasiri don rage lalacewar jijiyoyin ido.

Don warkar da ciwon sanyi, 1.2 g/rana na PEA shine daidaitaccen sashi.

Yi magana da likitanka kafin ɗaukar kari na PEA kamar yadda FDA ba ta amince da PEA don ɗaukar allurai da yawa ba.

Amfani da Palmitoylethanolamide foda ko kari a cikin ƙananan, ƙayyadaddun allurai galibi ana ɗaukar lafiya. Koyaya, ana buƙatar ƙarin ƙarin karatun asibiti don ƙarin allurai. Kariyar PEA na dogon lokaci kuma an san cewa yana da aminci bisa ga wasu ƙananan binciken.

Wasu masana'antun daga masana'antar kera PEA sun ba da shawarar raba jimlar kashi zuwa kashi biyu da cinye ta da rana. A wasu lokuta, micronized PEA, wanda a cikin kalmomi masu sauƙi yana da kyau palmitoylethanolamide foda, an san yana da kyau a cikin jiki kuma masana kimiyya suna ɗaukar nau'in foda ya fi sauran sifofi.

Abubuwan illa na PEA

Yawan shan palmitoylethanolamide ana ɗaukarsa lafiya ga yawancin manya idan aka yi amfani da shi har zuwa watanni 3. Har ya zuwa yau, ba a gano wata matsala mai tsanani ko hulɗar magunguna da magunguna ba. Koyaya, babu isasshen bayanin da zai ce maganin na iya zama lafiya lokacin amfani da shi sama da watanni uku. Gede effects na iya haɗawa da ciwon ciki, wanda ba kasafai ba ne.

Don ƙarin haske, PEA ba ta haifar da wata babbar matsala ba a kowane ɗayan karatun da ke sama amma har yanzu ba ta da ingantaccen binciken aminci. Har ila yau, babu isasshen shaidar da za a iya tantance adadin tasirin PEA a cikin marasa lafiya da ke da irin wannan ciwo.

Ciki da yara

PEA gabaɗaya ana ɗaukarta amintacciya don amfanin manya kuma wasu karatuttukan sun kuma nuna ƙarancin haɗari ga yara. Amma manyan karatun zasu buƙaci tabbatar da amincin PEA a cikin yara. Saboda rashin isasshen bayanan asibiti, ana ba da shawarar mata masu juna biyu da masu shayarwa su bi taka tsantsan tare da tuntubar likita kafin su ɗauki duk wani kari na PEA.

Kammalawa

PEA ta rage illoli masu yawa da zafi yayin inganta ingancin rayuwa. Karatunsa yana tallafawa aminci da ingancin acid mai ƙima kuma ana ba da shawarar amintattu a cikin amfani da asibiti na PEA. Ƙarin yana da tasiri sosai ga cututtukan matsawa ciki har da ciwon ramin carpal da ciwon sciatic. Haɗin PEA shima yana da sauƙin ɗauka kuma ana iya gudanar da shi da baki.

Ka tuna tuntuɓi likita kafin ɗaukar duk wani kari na PEA saboda mafi girman allurai na PEA na iya haifar da wasu matsaloli. Kodayake rikice -rikicen suna da sauƙi kuma ba su da mahimmanci, bai kamata a yi amfani da PEA a matsayin madadin hanyoyin likitanci da aka amince da su ba. Koyaya, fa'idodin da aka bayyana a sama an gudanar da su galibi a cikin dabbobi da sel. Tabbataccen shaidar asibiti har yanzu babu.

Ana buƙatar ƙarin karatu a cikin mutane don tantance tasirin PEA akan lafiyar hanji, zuciya, da sakin histamine.

Palmitoylethanolamide (PEA) foda don siyarwa & Inda za a sayi Palmitoylethanolamide (PEA) foda da yawa

Kamfaninmu yana jin daɗin dogon lokaci tare da abokan cinikinmu saboda muna mai da hankali kan sabis na abokin ciniki da kuma samar da mai girma kayayyakin. Idan kuna sha'awar samfuranmu, muna da sassauƙa tare da tsara umarni don dacewa da takamaiman buƙatarku kuma lokacin saurin jagorancinmu akan umarni yana bada tabbacin za ku ɗanɗana samfurinmu akan lokaci. Har ila yau, muna mai da hankali kan ƙarin sabis ɗin ƙimar. Muna nan don tambayoyin sabis da bayani don tallafawa kasuwancin ku.

Mu kwararre ne mai samar da Palmitoylethanolamide (PEA) foda na shekaru, muna ba da samfuran farashi mai tsada, kuma samfurinmu yana da inganci mafi kyau kuma yana yin tsauraran matakai, gwaji mai zaman kanta don tabbatar da cewa ba shi da haɗari ga amfani a duniya.

References

• Hansen HS. Palmitoylethanolamide da sauran mahaɗan anandamide. Matsayin da za'a gabatar dashi a kwakwalwar marassa lafiya. Exp Neurol. 2010; 224 (1): 48-55
• Petrosino S, Iuvone T, Di Marzo V. N-palmitoyl-ethanolamine: nazarin halittu da sabbin hanyoyin warkewa. Biochimie. 2010; 92 (6): 724-7
• Cerrato S, Brazis P, della Valle MF, Miolo A, Puigdemont A. Sakamakon cututtukan palmitoylethanolamide akan ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwayar cuta, PGD2 da TNFα daga sakin ƙwayar fata na canine. Vet Immunol Immunopathol. 2010; 133 (1): 9-15
• Palmitoylethanolamide (PEA): Fa'idodi, Sashi, Amfani, plementari

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