Nicotinamide Riboside Chloride (NR) (23111-00-4) Masana'antu - Cofttek

Nicotinamide Riboside chloride (NR) (23111-00-4)

Afrilu 7, 2020

Nicotinamide riboside, wanda kuma aka sani da NR da SRT647, nau'i ne na pyridine-nucleoside na bitamin B3 wanda ke aiki a matsayin mai farashi ga nicotinamide adenine dinucleotide ko NAD +. NR ta lalata lalacewar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar tsoka daga cikin jijiyoyin jiki da kuma kare kai daga saurin amo a cikin jijiyoyi masu rai.

 


Status: A Mass Production
Naúra: 1kg / jaka, 25kg / Drum

 

Nicotinamide Riboside Chloride (NR) (23111-00-4) bidiyo

 

Nicotinamide Riboside chloride (NR) Sfasali

name: Nicotinamide Riboside chloride (NR)
CAS: 23111-00-4
tsarki 98%
Formula kwayoyin: C11H15ClN2O5
Kwayoyin Weight: 290.7 g / mol
Shawarwar Melt: 115-125 ℃
Chemical name: 3-carbamoyl-1-((3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride
Kamancin: Nicotinamide riboside; SRT647; SRT-647; SRT 647; Nicotinamide Riboside Triflate, α / β cakuda
InChI Key: YABIFCKURFRPPO-FSDYPCQHSA-N
Rabin Rayuwa: 2.7 hours
Solubility: Matsala a cikin DMSO, Methanol, Ruwa
Yanayin Adana: 0 - 4 C don gajere (kwanaki zuwa makonni), ko -20 C na dogon lokaci (watanni)
Application: Nikotinamide riboside an yi ikirarin cewa shine sabon nau'i na pyridine-nucleoside na bitamin B wanda ke aiki a matsayin mai farashi zuwa nicotinamide adenine dinucleotide ko NAD +.
Appearance: Kashe Furu zuwa Kodadden Rawaya Foda

 

Menene Nicotinamide Riboside Chloride (NR) CAS 23111-00-4?

Nicotinamide riboside, wanda kuma aka sani da NR da SRT647, nau'i ne na pyridine-nucleoside na bitamin B3 wanda ke aiki a matsayin mai farashi ga nicotinamide adenine dinucleotide ko NAD +. NR ta lalata lalacewar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar tsoka daga cikin jijiyoyin jiki da kuma kare kai daga saurin amo a cikin jijiyoyi masu rai. Nicotinamide riboside yana hana tsoka, jijiya da melanocyte stem cell senescence. Beenara yawan farfadowa da tsoka a cikin jiji an lura dashi bayan an yi magani da riboside nicotinamide, har ya kai ga hasashe cewa yana iya inganta haɓaka gabobin kamar hanta, koda, da zuciya. Nicotinamide riboside shima yana rage girman glucose na jini da mai mai mai yawa a cikin wadanda ke fama da ciwon suga da nau'in masu ciwon sukari guda 2 yayin da yake hana haɓakar ciwan mai ciwon sukari. Lura: Nicotinamide Riboside chloride cakuda α / β ne.

 

 

Nicotinamide Riboside Chloride (NR) CAS 23111-00-4 amfanin

Nikotinamide nucleosides sune farkon abubuwan nicotinamide adenine dinucleotide (NAD) kuma suna wakiltar tushen bitamin B3. Binciken da aka yi kwanan nan ya nuna cewa ɗaukar mai yawa na nicotinamide nucleosides a zahiri a cikin abinci na iya samar da sabon fa'idodin kiwon lafiya. Misali, ana amfani da nicotinamide nucleosides a cikin kara yawan NAD nama da kuma gabatarda hankalin insulin tare da inganta aikin sirtuin. Itsarfinsa na haɓakar samar da NAD yana nuna cewa nicotinamide nucleosides na iya inganta lafiyar mitochondrial, haɓaka aikin mitochondrial, da kuma haifar da sabon ƙwayar mitochondria. Sauran nazarin da ake amfani da nicotinamide nucleosides a cikin ƙirar cutar ta Alzheimer sun nuna cewa kwayar halitta kwayar halitta ce zuwa ga kwakwalwa kuma tana iya samar da neuroprotection ta hanyar haɓaka ƙwaƙwalwar NAD.

Nicotinamide Riboside Chloride shima na iya Rage nauyi: Nazarin ya nuna cewa ta hanyar kara karfin kuzari, zaka iya rage cin abincin mai mai mai yawa wanda ya haifar da karuwar nauyi. Don kimanta tsarin ribose na nicotinamide na NR na inganta ƙimar nauyi, masu binciken sun auna aikin hanta mitochondrial wanda ke haɗuwa da cin abincin caloric, aiki, kalori, kewayen kugu, hutu na rayuwa, haɓakar jiki, haƙuri glucose, ƙwarewar insulin da nau'o'in biochemical da metabolomics sigogi Waɗannan bayanai da sabuwar hanyar rage nauyi ta hanyar malabsorption, ɓarkewar alamun halitta don bin diddigi. Masu binciken sun ba da rahoton cewa berayen da ke ciyar da abubuwan da ke amfani da nicotinamide sun kasance mafi kusantar rasa nauyi dangane da berayen da ba su da alaƙar nicotinamide

 

 

Nicotinamide Riboside Chloride (NR) CAS 23111-00-4 Hanyar Nauyi?

Nicotinamide Riboside Chloride (NR) nucleosides sune ƙaddarar nicotinamide adenine dinucleotide (NAD) kuma suna wakiltar tushen bitamin B3. Karatuttukan kwanan nan sun nuna cewa shan yawancin nicotinamide nucleosides da ke cikin abinci na iya samar da sabbin fa'idodin kiwon lafiya. Misali, nicotinamide nucleosides sun kasance suna da nasaba da karuwar narkar da nama ta NAD da kuma jawo hankalin insulin tare da inganta aikin sirtuin. Ikon sa na kara samar da NAD ya nuna cewa nicotinamide nucleosides na iya inganta lafiyar mitochondrial, karfafa aikin mitochondrial, da haifar da samar da sabon mitochondria. Sauran karatuttukan da ake amfani da su a cikin tsarin cutar Alzheimer na nicotinamide sun nuna cewa kwayar halittar ba ta cikin kwakwalwa kuma tana iya samar da kwayar cutar ta hanyar haɓaka kwakwalwa NAD kira ..

 

 

Nicotinamide Riboside Chloride (NR) CAS 23111-00-4 Aikace-aikace

Karatuttukan farko sun nuna cewa otarin nicotinamide ribose ba zai iya ƙara yawan NAD + ba cikin aminci, amma kuma yana ƙara yawan amfani da NAD + a cikin mutane, wanda hakan ba zai yiwu ba tare da sauran bitamin B3.Studies sun nuna cewa da zarar nicotinamide ribose ya bayyana a cikin tantanin halitta, jiki ya canza shi da sauri zuwa NAD +. Wadannan NAD + sannan suna kara aiwatar da ayyukan farawar cikin kwayar halitta ta hanyar samar da makamashi ta hanyar mitochondria

Nicotinamide Riboside Chloride na iya haɓaka aikin mitochondrial, wanda aka nuna don inganta maganganun jigilar sarkar sunadarai na mitochondrial, haɓaka yiwuwar ƙwaƙwalwar ƙwayar mitochondrial, da haɓaka adadin kuzarin oxidative da matakan ATP na ciki. Wannan na iya kasancewa tare da manyan matakan farfadowa na mitochondrial. Aikin Mitochondrial yana raguwa yayin da muke tsufa, kuma wannan shine alamar tsufa na sel da muke samu. NR na iya haɓaka aikin mitochondria kuma yana hana fitowar ƙwayoyin sel.

 

Nicotinamide Riboside chloride (NR) foda for sale(Inda Zaku sayi Nicotinamide Riboside Chloride (NR) foda a cikin tarin yawa)

Kamfaninmu yana jin daɗin haɗin kai tare da abokan cinikinmu saboda mun mai da hankali kan sabis na abokin ciniki da samar da samfuran manyan kayayyaki. Idan kuna da sha'awar samfurinmu, muna jujjuya tare da ƙirƙirar umarni don dacewa da takamaiman buƙatunku da lokacin jagoranmu na sauri akan umarni wanda zai ba ku tabbacin ku ɗanɗano samfurinmu akan lokaci. Hakanan muna mai da hankali kan ayyukan ƙara ƙimar. Muna samuwa don tambayoyin sabis da bayani don tallafawa kasuwancin ku.

 

Mu kwararren Nicotinamide Riboside Chloride (NR) mai samar da foda na shekaru da yawa, muna ba da samfuran farashi mai tsada, kuma samfurinmu yana da inganci mafi kyau kuma yana yin tsauraran matakai, gwaji mai zaman kanta don tabbatar da cewa ba shi da haɗari ga amfani a duniya.

 

References

  • Chi Y, Sauve AA. Nikotinamide riboside, mai gina jiki mai gina jiki a cikin abinci, shine bitamin B3 tare da tasiri akan metabolism na makamashi da neuroprotection. Curry Opin Clin Nutr Metab Kulawa. 2013 Nuwamba; 16 (6): 657-61. doi: 10.1097 / MCO.0b013e32836510c0. Dubawa. PubMed PMID: 24071780.
  • Bogan KL, Brenner C. Nicotinic acid, nicotinamide, da nicotinamide riboside: kimantawar kwayoyin NAD + takamaiman bitamin a cikin abincin mutum. Annu Rev Nutr. 2008; 28: 115-30. doi: 10.1146 / annurev.nutr.28.061807.155443. Dubawa. PubMed PMID: 18429699.
  • Ghanta S, Grossmann RE, Brenner C. Mitochondrial sunadarin protein na Mitochondrial a matsayin mai amfani da sikila, masanin juyin halitta na adana mai: sunadarai da dabaru na haɓakar acetyl-lysine. Crit Rev Biochem Mol Biol. 2013 Nuwamba-Dec; 48 (6): 561-74. doi: 10.3109 / 10409238.2013.838204. Dubawa. PubMed PMID: 24050258; PubMed Central PMCID: PMC4113336.
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