Mafi kyawun N-Acetyl-L-cysteine ​​ethyl ester (NACET) Manufacturer - Cofttek

N-Acetyl-L-cysteine ​​mai ladabi (NACET) (59587-09-6)

Bari 8, 2021

Cofttek shine mafi kyawun masana'antar foda N-Acetyl-L-cysteine ​​ethyl ester (NACET) a China. Masana'antarmu tana da cikakken tsarin sarrafa sarrafawa (ISO9001 & ISO14001), tare da damar samarwa kowane wata na 300kg.


Status: A Mass Production
Naúra: 1kg / jaka, 25kg / Drum

N-Acetyl-L-cysteine ​​ethyl ester (59587-09-6) Sfasali

name: N-Acetyl-L-cysteine ​​ethyl ester (NACET)
CAS: 59587-09-6
tsarki 98%
Formula kwayoyin: C7H13NO3S
Kwayoyin Weight: 191.25 g / mol
Shawarwar Melt: 197 zuwa 202 ° C
Chemical name: N-Acetyl-L-cysteine ​​ethyl ester

NACET (R) -ethyl 2-acetamido-3-mercaptopropanoate

Kamancin: N-Acetylcysteine ​​ethylester; (R) -Methyl 2-acetaMido-3-Mercaptopropanoate; -Ethyl 2-acetamido-3-mercaptopropanoate; Ethyl (2R) -2-Acetamido-3-Sulfanyl-Propanoate; (2R) -2-Acetamido-3-Mercaptopropanoic Acid Ethyl Ester; (2R) -2-Acetamido-3-Mercapto-Propionic Acid Ethyl Ester
InChI Key: MSMRAGNKRYVTCX-LURJTMIESA-N
Rabin Rayuwa: N / A
Solubility: Soluble cikin ruwa
Yanayin Adana: 0 - 4 C don gajere (kwanaki zuwa makonni), ko -20 C na dogon lokaci (watanni)
Application: N-Acetyl-L-cysteine ​​ethyl ester foda za a yi amfani da shi don haɓaka ƙwaƙwalwa, mayar da hankali, kerawa, hankali da kuma motsa hankali.
Appearance: Kashe-farin foda

 

N-Acetyl-L-cysteine ​​mai ladabi (NACET) (59587-09-6) Bayanin NMR

N-Acetyl-L-cysteine ​​ethyl ester (NACET) (59587-09-6) NMR bakan

Idan kuna buƙatar COA, MSDS, HNMR don kowane samfurin samfur da sauran bayanai, da fatan za a tuntuɓi mu manajan talla.

 

Menene N-Acetyl-L-cysteine ​​ethyl ester (NACET) (59587-09-6)?

N-Acetyl-L-cysteine ​​ethyl ester foda abu ne na halitta ko na roba wanda zai iya inganta aikin kwakwalwa, don inganta aikin tunani a cikin mutane masu lafiya. Yawancin lokaci ana kiran su Nootropics da ƙwayoyi masu kaifin baki, sun sami farin jini a cikin al'umma mai saurin gasa kuma galibi ana amfani dasu don haɓaka ƙwaƙwalwa, mai da hankali, kerawa, ƙwarewa da himma.

 

N-Acetyl-L-cysteine ​​ethyl ester (NACET) (59587-09-6) fa'idodi

Faɗakarwar ƙungiyar carboxyl don samar da N-acetylcysteine ​​ethyl ester yana ƙara yawan lipophilicity na NAC kuma yana inganta ingantaccen magungunan sa. NACET yana da haɓaka mafi girma (kusan 60%) fiye da NAC. NACET cikin hanzari ya shiga cikin sel, sa'annan ya kama, kuma ya rikida zuwa NAC da Cysteine. Ana samun NACET a cikin ƙwayoyin abubuwa daban-daban, gami da kwakwalwa saboda tana iya tsallake shingen ƙwaƙwalwar jini. NACET kuma tana samar da nau'ikan abubuwan kare lafiyar antioxidant. Ana iya ɗaukar NACET a baki kuma yana taimakawa haɓaka ƙoshin lafiya. Zai iya tarawa a cikin ɗan adam erythrocytes. NACET na iya yin aiki a matsayin mai kariya mai ƙarfi game da lalacewar sanadin hydroperoxide. NACA tana da ingantacciyar rayuwa fiye da NAC da kuma kwaya don inganta juriya da lokacin mazaunan bioscaffolds da biomaterials.

 

Brain

N-Acetyl-L-cysteine ​​ethyl ester foda 59587-09-6, abubuwa ne na halitta ko na roba waɗanda zasu iya haɓaka aikin kwakwalwa, don haɓaka aikin tunani. Yawancin lokaci ana kiran su Nootropics da ƙwayoyi masu kaifin baki, sun sami farin jini a cikin al'umma mai saurin gasa kuma galibi ana amfani dasu don haɓaka ƙwaƙwalwa, mai da hankali, kerawa, ƙwarewa da himma.

NACET tana kara yaduwar sinadarin hydrogen sulfide (H (2) S), don haka yana wakiltar kyakkyawan ɗan takara don amfani da baka a matsayin mai samar da H (2) S, tare da bayyana fifiko akan NAC.

Bayan maganin baka, NACET (amma ba NAC) ya sami damar haɓaka GSH abun ciki na yawancin kayan kyamara a cikin bera (gami da ƙwaƙwalwa), kuma ya kiyaye su daga maye na paracetamol.

 

Rashin Lafiya

Babban ƙungiyar bincike na farko ya nuna cewa ƙarin abinci tare da mai ƙarancin antioxidant N-acetylcysteine ​​(NAC) na iya hana kwayar cutar RNA da rage tsananin cututtukan da ke tattare da ita.

Wannan gyaran na NAC yana ba da izinin kariya daga ƙwayoyin jininka daga lalacewar oxidative, don haka ya ba da damar garkuwar jikinka ta kare jikinka da kyau daga ɓarnar COVID-19 (Wannan ba shawara ba ce ta likita). NAC kanta tana da ƙarancin bioavailability na baka saboda yana saurin haɗuwa a cikin hanta kafin ya isa jikin kyallenku, musamman huhun epithelium wanda yake mafi haɗari ga COVID-19 wanda ya haifar da lalacewar abu.

 

N-Acetyl-L-cysteine ​​mai ladabi (NACET) (59587-09-6) amfani?

Gwaje-gwaje na asibiti na kwanan nan sun kasa tabbatar da tasirin sakamako mai amfani da N-acetylcysteine ​​(NAC) wajen hana cututtukan da ke haifar da damuwa da damuwa. Wannan na iya zama saboda karancin ingancinsa. Muna tsammanin cewa rugujewar kungiyar ta carbonxyl ta NAC don samar da N-acetylcysteine ​​ethyl ester (NACET) zai iya ƙaruwa da ƙwaƙwalwar NAC sosai, don haka inganta haɓakar magunguna. A cikin aikin da muke ciki, muna ba da rahoto kan wakilcin sinadarai, kayan aikin magunguna da anti-oxidant na NACET, musamman a cikin kwatancen kai tsaye tare da NAC. Mun gano cewa NACET yana samun nutsuwa cikin hanzari bayan gudanar da magana amma ya kai mai rauni sosai cikin plasma. Wannan ya faru ne sabili da sifofi na musamman na NACET: yana saurin shiga sel zuwa inda aka tarko yana jujjuya shi zuwa NAC da cysteine. Bayan magani na baki, NACET (amma ba NAC ba) ya sami damar ƙara yawan abubuwan da ke cikin glutathione na yawancin kyallen takarda da aka bincika, kwakwalwa sun haɗa, kuma don kariya daga maye a cikin bera. NACET yana kuma da sifa ta musamman wanda zai iya tarawa a cikin halittun mutum inda yake nuna halaye mai ƙarfi akan lalata lalataccen abu mai lalatar da sinadarai. Nazarinmu ya nuna cewa samun damar shiga sel kuma don samar da NAC da cysteine, NACET yana haɓaka haɓakar hydrogen sulfide (H (2) S), don haka yana wakiltar ɗan takara mai kyau don amfani da baka a matsayin mai samar da H (2) S, tare da tabbatattun fa'idodi sama da NAC. NACET yana da damar maye gurbin NAC a matsayin wakili na mucolytic, a matsayin maganin paracetamol kuma a matsayin maganin antioxidant na GSH.

 

N-Acetyl-L-cysteine ​​mai ladabi (NACET) (59587-09-6) Aikace-aikace

NACET (N-Acetylcysteine ​​ethyl ester) wani abu ne wanda aka samo asali na lipophilic cell-permeable cysteine ​​cysteine ​​tare da wani sabon nau'in sikandire na likitancin magani da kuma kyamar maganin antioxidant. NACET yana da bioavailability mai tsayi na baki. Dogaro ne mai mahimmanci na antioxidant kuma mai wadatarwa na GSH, wanda ke da alaƙa da sinadarin acid na N-acetyl -L ya bambanta da -cysteine ​​(NAC). NACET farin farar foda ne a zazzabi a daki kuma yana narkewa cikin ruwa da sinadarai.

NAC asali ne na cysteine. Tun daga shekarun 1970, ana amfani da shi don kula da marasa lafiya tare da maganin hana ƙwayoyin cuta na acetaminophen da raunin jijiyoyin jiki, kuma ana tallata shi azaman magani da ƙari na abinci. Idan aka kwatanta da NAC, NACET yana da mafi yawan lipophilicity da ingantattun kayan magunguna. Yana da damar maye gurbin NAC na pharmacological, a matsayin wakili na mucolytic, antioxidant, mai ba da kyautar GSH, paracetamol antidote, kuma aƙalla Donor na mai ba da jijiyoyin H 2 S da wakilin kariya na UV.

Kari akan haka, an tabbatar da karfin nucleophilicity da rage karfin NACET a cikin kwayoyin halittar jini na mutum. An samo shi don tarawa cikin sel jini na mutum, yana tsayayya da lalacewa ta hanyar lalacewa ta hanyar hydroperoxides. Saboda haka, yuwuwar NACET a matsayin ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta ta ƙasa mafi girma fiye da ta NAC methemoglobinemia da sauran abubuwa masu ƙarfi. Nazarin cikin berayen sun gano cewa NACET yana da sauri sosai fiye da NAC yayin da ake sarrafa NACET ta baka. Zai iya shiga cikin sel kuma ya samar da NAC da cysteine, wanda ke haɓaka hydrogen sulfide (H (2) S) a cikin kewaya. Kyakkyawan ɗan takara ne don yin amfani da baka a matsayin mai samar da H (2),

 

NACET foda for sale(Inda zaka sayi NACET foda a girma)

Kamfaninmu yana jin daɗin haɗin kai tare da abokan cinikinmu saboda mun mai da hankali kan sabis na abokin ciniki da samar da samfuran manyan kayayyaki. Idan kuna da sha'awar samfurinmu, muna jujjuya tare da ƙirƙirar umarni don dacewa da takamaiman buƙatunku da lokacin jagoranmu na sauri akan umarni wanda zai ba ku tabbacin ku ɗanɗano samfurinmu akan lokaci. Hakanan muna mai da hankali kan ayyukan ƙara ƙimar. Muna samuwa don tambayoyin sabis da bayani don tallafawa kasuwancin ku.

Mu ƙwararren mai samarda NACET ne na samarda foda na tsawon shekaru, muna samar da kayayyaki da farashi mai fa'ida, kuma samfuran mu yana da inganci kuma yana fuskantar tsayayye, gwaji mai zaman kansa don tabbatar da cewa amintacce ne don amfani a duk duniya.

 

References

[1] N-acetylcysteine ​​ethyl ester a matsayin GSH mai haɓakawa a cikin ƙwayoyin endothelial na ɗan adam: Nazarin kwatancen tare da wasu kwayoyi. 2018 Oct; 126: 202-209. doi: 10.1016 / j.freeradbiomed.2018.08.013. Epub 2018 Aug 14. PMID: 30114478.

[2] N-acetylcysteine ​​ethyl ester a matsayin GSH mai haɓakawa a cikin ƙwayoyin endothelial na ɗan adam: Nazarin kwatancen tare da wasu kwayoyi. 2018 Oct; 126: 202-209. doi: 10.1016 / j.freeradbiomed.2018.08.013. Epub 2018 Aug 14. PMID: 30114478.

[3] S-Nitroso-N-acetyl-L-cysteine ​​ethyl ester (SNACET) da N-acetyl-L-cysteine ​​ethyl ester (NACET) - candidatesan takarar yan asalin ƙwayoyin Cysteine ​​tare da keɓaɓɓun bayanan magunguna don amfani da baki kamar NO, H2S da masu samar da GSH da azaman antioxidants: Sakamako da bayyani. 2018 Feb; 8 (1): 1-9. Doi: 10.1016 / j.jpha.2017.12.003. Epub 2017 Dec 13. Dubawa. PMID: 29568662.