FREE RADICAL ka'idar

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Tsarin jiki na al'ada

Sanin iska

Ultraviolet radiation

Karfin karfe mai nauyi

Gurbataccen maganin ƙwari

Gurbataccen maganin ƙwari

 

 

FREE RADICALS & cuta

 

A yadda aka saba, 'yanci masu kyauta suna da mahimmanci ga jiki, amma masu kyauta masu kyauta na iya haifar da rashin daidaituwa a aikin ilimin lissafi, sa'annan ya haifar da gajiya mai narkewa a cikin cututtuka daban-daban (wallafe-wallafe suna nuna cewa masu kyauta ba su da tushe daban-daban)

 

 

 

 

MAI GABATARWA

 

Jikinmu ba zai iya aiki ba tare da iskar oxygen ba, kuma da zarar adadi mai yawa na masu raɗaɗi kyauta ya karu, jiki a ƙarƙashin matsi mai raɗaɗi zai haifar da tsarin gyarawa ya gaza wajen cire matsanancin radicals. A cikin lamura na musamman, jiki yana buƙatar cika antioxidants a cikin vitro don cire matsanancin free radicals.

 

CIGABA DA MAGANGANUN MUTANE

 

 

L-ERGOTHIONINE –SABON IRIN NA DAN ADAM

 

Misali shine amino-acid antioxidant antioxidant biosynthesized a cikin wasu kwayoyin cuta da fungi. Yana da wani muhimmin sinadarin bioactive wanda aka yi amfani dashi azaman mai tsattsauran ra'ayi, mai tace rayukan ultraviolet, mai kula da halayen rage hawan abu da kuma bioenergetics na salula, da kuma ilimin kimiyyar lissafi, da dai sauransu.
L-Ergothioneine (EGT, ERGO, CAS: 497-30-3), wanda kuma aka sani da (S) -α-Carboxy-2,3-dihydro-N, N, N-trimethyl-2-thioxo-1H-imidazole- 4-ethanaminium gishirin ciki, da farko Tanret C ya fitar dashi daga barna a cikin 1909, sannan kuma an gano shi a cikin jinin dabba. EGT mai tsabta farin lu'ulu'u ne, mai narkewa cikin ruwa, (narkar da 0.9mol / L a zazzabi a daki). Autoxidation ba zai iya faruwa ba a kimar lissafin ilimin halittu ko cikin maganin alkaline mai ƙarfi. EGT zai iya wanzu a cikin nau'i biyu na isomer - nau'i na thiol da thione, kamar yadda aka nuna a ƙasa:

 

 

 

MAGUNGUNA

Tare da fa'idodi na ayyuka da yawa, Misali ya fita waje tsakanin sauran antioxidants.

 

 

abũbuwan amfãni

Tare da fa'idodi na ayyuka da yawa, EGT yayi fice tsakanin sauran mutane antioxidantsAbubuwan amfani (idan aka kwatanta da glutathione, cysteine ​​da dai sauransu):
——EGT ya fi sauƙi a tara cikin ƙwayoyin cuta kuma natsuwa ya fi kwanciyar hankali fiye da sauran antioxidants.
——EGT ya fi tasiri akan rage mutuwar ƙwayoyin sel wanda Pyrogallol ya haifar.
——EGT galibi yana ragargaza ROS don hana haɓakar abu, yayin da glutathione da sauransu ke ba da kariya ga masu kyauta, wato, sauran antioxidants Samfuran samfur.(1) Oleoylethanolamide (oea) - sihiri ne na rayuwarka

Kwatantawa da ANTIOXIDATION

results: Misali ya kasance mafi yawan masu yaduwa na kyauta kamar yadda aka kwatanta da antioxidants na gargajiya kamar GSH, uric acid da trolox. Musamman, mafi girman ƙarfin antioxidant wanda EGT vs. peroxyl radicals ya nuna ya haifar da 25% mafi girma fiye da ƙimar da aka samu tare da maganin antioxidant antioxidant. Thearfin haɓaka EGT zuwa masu tsinkayen hydroxyl ya kasance 60% mafi girma, idan aka kwatanta da uric acid, wanda ke wakiltar maganin antioxidant vs. hydroxyl radicals. A ƙarshe, EGT ya nuna aikin antioxidant mafi girma kuma zuwa ga peroxynitrite, tare da ƙarfin haɓaka 10% mafi girma fiye da na uric acid.

 

 

 

SAURAN SAURARA

 

Hakanan EGT yana da tasiri kan daidaita karfin kuzarin ciki,

inganta rigakafi,

haɓaka ƙimar ƙwayar maniyyi,

kare hanta daga rauni,

hana kumburi,

sabbinna,

lahani na haɓaka da kamuwa da cuta.

 

 

WAJIBAN CIGABA

① AN SAMU EGT CIKIN YADU CIKIN SHIRI DA Dabbobi

 

② Umarni

5-10mg kowace sashi don manya da 2-3 ci gaba da ci yana da mahimmanci a cikin abincinku na yau da kullun.

Source: Li Yiqun, Zhou Nianbo. Ayyukan Biology da Aikace-aikacen EGT [J]. Injiniyan Abinci , 2010,9 (3) : 26-28.

An jera abubuwan shiga kamar haka:

Yara (shekaru 3-11) 0l XNUMX MG / rana
Matasa (shekaru 11-21) Mg30 MG / rana
Manya (shekaru 21-80) Mg30 MG / rana

Lura : 1. Abubuwan asibiti don yara da manya (3 -80 shekara)

           Ba a ba da shawarar amfani da mata masu ciki ko masu shayarwa.

Bayanin bayanan: Tetrahedron lokacin da ake nema don US NDI

Bayanai suna ba da shawara: 10.5mg / g don OXIS's ADI (Amincewa da Daily).

 

YN TAIMAKO

 

 

FITARWA & AIKI

(1) FITARWA

A halin yanzu, akwai hanyoyi guda uku don samar da EGT: hada sinadarai, halitta bio-hakar (yawanci daga namomin kaza, kayan dabbobi da hakar jini), da kuma hanyar biosynthesis.

Kwatanta Haɗin EGT Hanyar

(2) AIKI

EGT yana da aikace-aikace masu yawa a cikin kayan shafawa, abinci abinci, likitancin magani, warkewa, biomedicine, da sauransu.

(3) SAURAN AIKI

References

  1. Oleoylethanolamide (oea) - sihiri ne na rayuwarka
  2. Anandamide vs cbd: wanne ne ya fi dacewa da lafiyar ku? Duk abin da kuke buƙatar sani game da su!
  3. Duk abin da kuke buƙatar sani game da nicotinamide riboside chloride
  4. Magnesium l-threonate kari: fa'idodi, sashi, da sakamako masu illa
  5. Palmitoylethanolamide (fis): fa'idodi, sashi, amfani, kari
  6. Manyan fa'idodin kiwon lafiya na 6 na resveratrol
  7. Manyan fa'idodi guda 5 na shan phosphatidylserine (ps)
  8. Manyan fa'idodi guda 5 na shan pyrroloquinoline quinone (pqq)
  9. Mafi kyawun nootropic na alpha gpc
  10. Mafi kyawun kariyar tsufa na nicotinamide mononucleotide (nmn)

 

Labari na. Dr. Zeng

Mataki na ashirin da:

Dakta Zeng

Co-kafa, babban shugabancin kamfanin; PhD ta karɓa daga Jami'ar Fudan a cikin ilimin sunadarai. Fiye da shekaru tara na ƙwarewa a cikin ilimin sunadarai da ƙirar ƙirar ƙwayoyi; kusan takardun bincike 10 da aka buga a cikin mujallu masu iko, tare da lasisin mallakar Sinawa sama da biyar.

 

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